Yang Li Lab - Publications

Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi (Li, Yang, Oosting, Marije, Deelen, Patrick, Ricaño-Ponce, Isis, Smeekens, Sanne, Jaeger, Martin, Matzaraki, Vasiliki, Swertz, Morris A., Xavier, Ramnik J., Franke, Lude, Wijmenga, Cisca, Joosten, Leo A. B., Kumar, Vinod and Netea, Mihai G.), In Nature Medicine, volume 22, 2016.
A Functional Genomics Approach to Understand Variation in Cytokine Production in Humans (Li, Yang, Oosting, Marije, Smeekens, Sanne P., Jaeger, Martin, Aguirre-Gamboa, Raul, Le, Kieu T. T., Deelen, Patrick, Ricaño-Ponce, Isis, Schoffelen, Teske, Jansen, Anne F. M., Swertz, Morris A., Withoff, Sebo, van de Vosse, Esther, van Deuren, Marcel, van de Veerdonk, Frank, Zhernakova, Alexandra, van der Meer, Jos W. M., Xavier, Ramnik J., Franke, Lude, Joosten, Leo A. B., Wijmenga, Cisca, Kumar, Vinod and Netea, Mihai G.), In Cell, volume 167, 2016.
Differential Effects of Environmental and Genetic Factors on T and B Cell Immune Traits (Aguirre-Gamboa, Raul, Joosten, Irma, Urbano, Paulo C. M., van der Molen, Renate G., van Rijssen, Esther, van Cranenbroek, Bram, Oosting, Marije, Smeekens, Sanne, Jaeger, Martin, Zorro, Maria, Withoff, Sebo, van Herwaarden, Antonius E., Sweep, Fred C. G. J., Netea, Romana T., Swertz, Morris A., Franke, Lude, Xavier, Ramnik J., Joosten, Leo A. B., Netea, Mihai G., Wijmenga, Cisca, Kumar, Vinod, Li, Yang and Koenen, Hans J. P. M.), In Cell Reports, volume 17, 2016.
Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses (Bakker, Olivier B., Aguirre-Gamboa, Raul, Sanna, Serena, Oosting, Marije, Smeekens, Sanne P., Jaeger, Martin, Zorro, Maria, Võsa, Urmo, Withoff, Sebo, Netea-Maier, Romana T., Koenen, Hans J. P. M., Joosten, Irma, Xavier, Ramnik J., Franke, Lude, Joosten, Leo A. B., Kumar, Vinod, Wijmenga, Cisca, Netea, Mihai G. and Li, Yang), In Nature Immunology, volume 19, 2018.
Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment (Schulte-Schrepping, Jonas, Reusch, Nico, Paclik, Daniela, Baßler, Kevin, Schlickeiser, Stephan, Zhang, Bowen, Krämer, Benjamin, Krammer, Tobias, Brumhard, Sophia, Bonaguro, Lorenzo, De Domenico, Elena, Wendisch, Daniel, Grasshoff, Martin, Kapellos, Theodore S., Beckstette, Michael, Pecht, Tal, Saglam, Adem, Dietrich, Oliver, Mei, Henrik E., Schulz, Axel R., Conrad, Claudia, Kunkel, Désirée, Vafadarnejad, Ehsan, Xu, Cheng-Jian, Horne, Arik, Herbert, Miriam, Drews, Anna, Thibeault, Charlotte, Pfeiffer, Moritz, Hippenstiel, Stefan, Hocke, Andreas, Müller-Redetzky, Holger, Heim, Katrin-Moira, Machleidt, Felix, Uhrig, Alexander, Bosquillon de Jarcy, Laure, Jürgens, Linda, Stegemann, Miriam, Glösenkamp, Christoph R., Volk, Hans-Dieter, Goffinet, Christine, Landthaler, Markus, Wyler, Emanuel, Georg, Philipp, Schneider, Maria, Dang-Heine, Chantip, Neuwinger, Nick, Kappert, Kai, Tauber, Rudolf, Corman, Victor, Raabe, Jan, Kaiser, Kim Melanie, Vinh, Michael To, Rieke, Gereon, Meisel, Christian, Ulas, Thomas, Becker, Matthias, Geffers, Robert, Witzenrath, Martin, Drosten, Christian, Suttorp, Norbert, von Kalle, Christof, Kurth, Florian, Händler, Kristian, Schultze, Joachim L., Aschenbrenner, Anna C., Li, Yang, Nattermann, Jacob, Sawitzki, Birgit, Saliba, Antoine-Emmanuel, Sander, Leif Erik, Angelov, Angel, Bals, Robert, Bartholomäus, Alexander, Becker, Anke, Bezdan, Daniela, Bonifacio, Ezio, Bork, Peer, Clavel, Thomas, Colome-Tatche, Maria, Diefenbach, Andreas, Dilthey, Alexander, Fischer, Nicole, Förstner, Konrad, Frick, Julia-Stefanie, Gagneur, Julien, Goesmann, Alexander, Hain, Torsten, Hummel, Michael, Janssen, Stefan, Kalinowski, Jörn, Kallies, René, Kehr, Birte, Keller, Andreas, Kim-Hellmuth, Sarah, Klein, Christoph, Kohlbacher, Oliver, Korbel, Jan O., Kurth, Ingo, Landthaler, Markus, Li, Yang, Ludwig, Kerstin, Makarewicz, Oliwia, Marz, Manja, McHardy, Alice, Mertes, Christian, Nöthen, Markus, Nürnberg, Peter, Ohler, Uwe, Ossowski, Stephan, Overmann, Jörg, Peter, Silke, Pfeffer, Klaus, Poetsch, Anna R., Pühler, Alfred, Rajewsky, Nikolaus, Ralser, Markus, Rieß, Olaf, Ripke, Stephan, Nunes da Rocha, Ulisses, Rosenstiel, Philip, Saliba, Antoine-Emmanuel, Sander, Leif Erik, Sawitzki, Birgit, Schiffer, Philipp, Schulte, Eva-Christina, Schultze, Joachim L., Sczyrba, Alexander, Stegle, Oliver, Stoye, Jens, Theis, Fabian, Vehreschild, Janne, Vogel, Jörg, von Kleist, Max, Walker, Andreas, Walter, Jörn, Wieczorek, Dagmar and Ziebuhr, John), In Cell, volume 182, 2020.
Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease (Chu, Xiaojing, Jaeger, Martin, Beumer, Joep, Bakker, Olivier B., Aguirre-Gamboa, Raul, Oosting, Marije, Smeekens, Sanne P., Moorlag, Simone, Mourits, Vera P., Koeken, Valerie A. C. M., de Bree, Charlotte, Jansen, Trees, Mathews, Ian T., Dao, Khoi, Najhawan, Mahan, Watrous, Jeramie D., Joosten, Irma, Sharma, Sonia, Koenen, Hans J. P. M., Withoff, Sebo, Jonkers, Iris H., Netea-Maier, Romana T., Xavier, Ramnik J., Franke, Lude, Xu, Cheng-Jian, Joosten, Leo A. B., Sanna, Serena, Jain, Mohit, Kumar, Vinod, Clevers, Hans, Wijmenga, Cisca, Netea, Mihai G. and Li, Yang), In Genome Biology, volume 22, 2021.
Cell-type eQTL deconvolution of bronchial epithelium through integration of single-cell and bulk RNA-seq (Qi, Cancan, Berg, Marijn, Chu, Xiaojing, Timens, Wim, Kole, Tessa, van den Berge, Maarten, Xu, Cheng-Jian, Koppelman, Gerard H., Nawijn, Martijn C. and Li, Yang), In Allergy, volume 77, 2022.
Single-cell RNA sequencing reveals induction of distinct trained-immunity programs in human monocytes (Zhang, Bowen, Moorlag, Simone J. C. F. M., Dominguez-Andres, Jorge, Bulut, Özlem, Kilic, Gizem, Liu, Zhaoli, Crevel, Reinout van, Xu, Cheng-Jian, Joosten, Leo A. B., Netea, Mihai G. and Li, Yang), In The Journal of Clinical Investigation, volume 132, 2022.
Single-cell profiles reveal distinctive immune response in atopic dermatitis in contrast to psoriasis (Zhang, Bowen, Roesner, Lennart M., Traidl, Stephan, Koeken, Valerie A. C. M., Xu, Cheng-Jian, Werfel, Thomas and Li, Yang), In Allergy, volume 78, 2023.
Altered and allele-specific open chromatin landscape reveals epigenetic and genetic regulators of innate immunity in COVID-19 (Zhang, Bowen, Zhang, Zhenhua, Koeken, Valerie A. C. M., Kumar, Saumya, Aillaud, Michelle, Tsay, Hsin-Chieh, Liu, Zhaoli, Kraft, Anke R. M., Soon, Chai Fen, Odak, Ivan, Bošnjak, Berislav, Vlot, Anna, Swertz, Morris A., Ohler, Uwe, Geffers, Robert, Illig, Thomas, Huehn, Jochen, Saliba, Antoine-Emmanuel, Sander, Leif Erik, Förster, Reinhold, Xu, Cheng-Jian, Cornberg, Markus, Schulte, Leon N. and Li, Yang), In Cell Genomics, volume 3, 2023.